Toyo 888

Has anyone seen this before with 888s?

Raised up bits. Part of the tyre they can’t be removed.
 

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They've just got a bit hot and the edge has pulled away on the tread block. Completely normal.

Be gone as soon as you go on track again.
 
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It is the unsupported edge of rubber that folds into the tread void from the side that the load is applied to. Because that folds into, or more so there is nothing supporting the rubber at that point it is not subject to the same load as the more solid rubber and so does not wear as much. It is usually matched on the opposite side of the tread void with a rounded edge as that area is subject to load and goes "blunt" just like any square edge would. Cornering is usually along the axis of the tyre. You seem to have a fair amount there due to braking as well which is radial and in the leading edge of the block.